Though treatments are available, there is no cure or vaccine from HIV, which impacts about 38 million people worldwide. It's difficult to target the RNA genome of the HIV virus in part because it ...

Scientists at the Electron Bio-Imaging Centre (eBIC) at Diamond Light Source, in the U.K., have harnessed a new technique, using cryo-electron tomography (cryoET) and subtomogram averaging (STA) to ...

Researchers report that they have determined the precise chemical structure of the HIV capsid, a protein shell that protects the virus's genetic material and is a key to its virulence. The capsid has ...

The outer shells – or capsids – of viruses contain proteins, which are made of a string of building blocks called amino acids. Proteins fold into specific shapes, depending on the sequence of amino ...

A new technique using electron tomography and subtomogram averaging at Diamond's electron Bio-Imaging Centre (eBIC), has solved the structure of the HIV capsid alone and in complex with host factors.

In a mature, infectious HIV-1 virion, the viral genome is housed within a conical capsid core made up of the viral capsid (CA) protein. During infection, the CA protein interacts with several cellular ...

Herpesviruses are a leading cause of human viral diseases, including oral and genital blisters (herpes simplex viruses HSV-1 and HSV-2), chicken pox and shingles (varicella zoster virus), and cancers ...

Cryo-electron microscopy has given scientists the first glimpse at how the measles virus wraps up its genome in its protective protein container. The 4.3-Å structure provides a platform for ...

Today’s comment of the day comes to us from commenter Ryan M, who responded to our call for the most incredible images of 2013 with a nominee from something that he’s been working on: The first look ...

With up to 2.4 million U.S. cases and over 250 million chronic cases globally, hepatitis B infection persists despite the availability of a vaccine. Vaccines work by immunizing the body against a ...

Paramecium bursaria Chlorella virus type 1 (PBCV-1) is a very large, icosahedral virus containing an internal membrane enclosed within a glycoprotein coat consisting of pseudohexagonal arrays of ...