Hydroxyzine is a commonly prescribed antihistamine used to treat allergies, itching, and anxiety. Hydroxyzine can interact with various medications and substances, including central nervous system ...

To learn more about these conditions and how hydroxyzine is used for them, see the “What is hydroxyzine used for?” section below. Hydroxyzine is classified as an antihistamine. You’ll take hydroxyzine ...

Hydroxyzine (whose brand names include Vistaril) and Benadryl (the brand name of diphenhydramine) are both first-generation antihistamines and share many similarities, including sedating side effects.