Larger animal models, such as porcine, have been validated as appropriate models of the human disc with respect to biomechanics and biochemistry. They are advantageous for research as the models are ...

FibroBiologics (FBLG) announced preclinical results for FSdC, an investigational FSdC spheroid-based therapy, demonstrating superior improvement ...

A biomechanical model of a simple lifting motion is presented in which the forces and moments of force acting about the L4-L5 vertebral articulation were determined from kinetic and kinematic data.

As people get older, the intervertebral discs in their spine tend to deteriorate, some of which end up being surgically replaced with implants. A new patient-specific spinal model, however, could help ...

March 22, 2007 — Preliminary experience in 5 patients with degenerative spine disease suggests that transplantation of fresh-frozen intervertebral disks preserved motion and stability of the spinal ...

IVDD involves disc herniation or rupture, causing spinal cord compression with varying severity, from pain to paralysis. Breeds like Dachshunds are predisposed, but factors like obesity and trauma ...

Degenerative disc disease is when one or more of the discs between the vertebrae of the spinal column deteriorate or break down, leading to pain. There may be weakness, numbness, and pain that ...

The intervertebral disc is a fibrous tissue that provides a jelly-like cushion between the bones of the spine. These discs provide your dog's spine with the flexibility that helps them move, run, and ...

FibroBiologics is pursuing a development program for FSdC spheroids with the goal of advancing to clinical trials. The data includes comprehensive preclinical pharmacology and efficacy assessments ...