The study protocol was approved by the Institutional Review Board of MetroHealth Medical Center, Cleveland, Ohio. All studies were carried out after obtaining verbal assent from the attending ...
Viral proteins reprogram several processes associated with primary metabolism by interacting with the host’s metabolic enzymes. The methionine cycle (MTC), also known as activated methionine cycle, is ...
APAP-induced DILI leads to dysregulation of ammonia levels. The negative modulation of miR-873-5p restores methionine cycle activity, attenuates ammonia accumulation, and increases polyamine synthesis ...
DHFR: dihydrofolate reductase; FH2: dihydrofolic acid; FH4: tetrahydrofolic acid; MTHFD: methylenetetrahydrofolate dehydrogenase; SHMT: hydroxymethyltransferase ...
Some brain cancers are easier to treat than others, and while many solid tumors can be removed surgically, others, such as diffuse midline gliomas (DMGs), are much trickier. The results of studies in ...
Methionine is an amino acid that is used to build molecules important for cell and DNA function. Meat, eggs, fish, and other foods containing protein will have some methionine in them. Amino acids ...
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