Reducing the time and expense of engineering PROTAC degraders remains a significant challenge in the pharmaceutical industry. A PROTAC is composed of an E3 ligase ligand (E3-L), a protein of interest ...
The University of Michigan has published details on the discovery and preclinical characterization of a new potent and selective proteolysis targeting chimera (PROTAC) degrader of BRD9, CW-3308.
This article and associated images are based on a poster originally authored by Poppy Wood, James Craswell, Holly Madden, Alicia Galvan-Alvarez, Gabriel Negoita-Giras, David Gibson, Scarlett Turner, ...
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