Integration of a cDNA copy of the viral RNA genome is essential to establish infection by retroviruses. This process (see, for example, ref. 10 for a review) is catalysed by the virus-encoded enzyme ...
All retroviruses — except spumaretroviruses — efficiently select and package two copies of their full-length RNA genomes as they assemble in infected cells. The nucleocapsid (NC) domains of the ...
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