Researchers have engineered a next-generation glutamate sensor, iGluSnFR4, capable of detecting the faintest incoming ...

Ketamine is a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist that produces rapid antidepressant action in some patients with treatment-resistant depression. However, recent data ...

A new protein sensor lets researchers see incoming brain signals, revealing how neurons process information tied to memory ...

Increased levels of bioactive lipids produced naturally in the body, which affect excitatory transmission between brain cells, promote mental disorders. However, this mechanism can be rebalanced by ...

Engineers are starting to build hardware that does not just run artificial intelligence, it behaves like a primitive form of ...

Northwestern Medicine scientists have discovered that targeting neuronal signaling controlling aberrant learning in the ...

Parkinson's and Alzheimer's diseases are the two most common neurodegenerative disorders, affecting millions of people worldwide. Published in the Journal of Neuroscience, new research from the ...

A) Taste tissue of wild-type mice and taste cell synaptic dysfunction mice (SNAP-cKO). In SNAP-cKO mice, the number of sour-sensing cells is reduced. B) Gustatory nerve responses to various taste ...

Neurons intertwine with small blood vessels in the brain, but how do the two communicate? With elaborate three-dimensional reconstructions of electron microscopy images, scientists led by Jie-Min Jia, ...

The rapid influx of cerebral spinal fluid (CSF) and protein solutes released during cortical spreading depression (CSD) in the brain activates neurons to trigger aural migraine headaches, according to ...