Adipocytokines are usually regarded as signaling molecules that originate from and act within the adipose tissue. However, recent data show that adipocytokines, especially adiponectin, exert various ...

Obesity is one of the greatest burdens of global public health. One major factor that drives obesity is excessive fat accumulation. Despite decades of research, the biological processes that trigger ...

Figure 1: HCM mutant αTm structure and expression. The direct increase myofilament calcium sensitivity associated with HCM mutations in α-Tm reported here is in contrast to effects seen with HCM ...

A conserved signaling axis linking Drosophila adipose tissue to nephrocyte function reveals how obesity can drive kidney dysfunction and points to new opportunities for therapeutic intervention.