This article and associated images are based on a poster originally authored by Poppy Wood, James Craswell, Holly Madden, Alicia Galvan-Alvarez, Gabriel Negoita-Giras, David Gibson, Scarlett Turner, ...
Reducing the time and expense of engineering PROTAC degraders remains a significant challenge in the pharmaceutical industry. A PROTAC is composed of an E3 ligase ligand (E3-L), a protein of interest ...
Pfizer, Arvinas lose interest in commercializing PROTAC inhibitor, leading to layoffs at the biotech
Having already stripped back their development plans for the estrogen receptor (ER) degrader vepdegestrant on the back of mixed data, Pfizer and Arvinas have now decided to wash their hands of the ...
As an added bonus, ProTac can be set to a "flicker mode" in which the PDLC continuously (and rapidly) switches back and forth between its transparent and opaque states. This allows the system to ...
Conceptual overview of the vision-based ProTac sensing technology. ProTac can actively switch between proximity and tactile sensing modes, relying on input images captured by inner cameras and a soft ...
CHENGDU, China--(BUSINESS WIRE)--HitGen and Fierce Biotech jointly release the Whitepaper: Advancing Drug Discovery through DNA-Encoded Library (DEL) Technology today. This whitepaper will provide the ...
In this phase 3, open-label, randomized trial, we enrolled patients with ER-positive, human epidermal growth factor receptor 2 (HER2)–negative advanced breast cancer who had received one previous line ...
A new discovery could pave the way for more effective cancer treatment by helping certain drugs work better inside the body. Scientists at Duke University School of Medicine, University of Texas ...
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