Antithrombin (AT) is a small glycoprotein that inactivates several enzymes of the coagulation system. It is a 464-amino-acid protein produced by the liver.

Jul 22, 2023 · Antithrombin is a protein in our blood, which functions as a naturally occurring anticoagulant. It is like a police protein that prevents us from clotting too much. It blocks our blood …

Antithrombin is a plasma protein that inhibits thrombin and factors Xa, IXa, and XIa, thereby inhibiting thrombosis. Heterozygous deficiency of antithrombin has a prevalence of approximately 0.02 to 0.2% …

Antithrombin (AT), also known as antithrombin III, is defined as a naturally occurring protease inhibitor that maintains balance in the coagulation system by inactivating various coagulation factors, …

Nov 23, 2021 · Antithrombin (antithrombin III) deficiency is a blood clotting problem that can put you at risk for a dangerous blood clot. When you have this deficiency, clotting can continue without enough …

Nov 28, 2025 · Antithrombin is a protein manufactured by the liver and circulated throughout the blood plasma, where it acts as a primary component of the body’s defense against excessive clotting.

Aug 27, 2025 · Deficiency of antithrombin (AT; antithrombin III) can be inherited or acquired; it is defined as an AT activity level that is consistently less than 80 percent of normal (or the lower limit of the …

Antithrombin works as a mild blood thinner so that the blood doesn't clot too much. A lack of antithrombin (AT) can make it more likely for you to form blood clots.

Antithrombin is a protein produced by the liver to help control blood clotting. Normally, when a blood vessel is injured, the body activates a series of coagulation factors, in a process called the …

In addition to being an anticoagulant serpin by inhibiting the proteolytic activity of coagulation proteases of both intrinsic and extrinsic pathways, antithrombin (AT) also exhibits potent anti-inflammatory …